|
KMID : 0371420200980040184
|
|
Annals of Surgical Treatment and Research
2020 Volume.98 No. 4 p.184 ~ p.189
|
|
|
The efficacy of 18F-FDG PET/CT in the preoperative evaluation of pancreatic lesions
|
|
Akcam Atilgan Tolga
Teke Zafer
Saritas Ahmet Gokhan
Ulku Abdullah
Guney Isa Burak
Rencuzogullari Ahmet
|
|
|
Abstract
|
|
|
Purpose: Since the treatment strategy for benign and malignant pancreatic lesions differ, we aimed to evaluate the clinical value of PET/CT in the diagnosis and management of pancreatic lesions.
Methods: Ninety patients who had a histologically confirmed pancreatic lesion were studied. Receiver operating characteristic (ROC) curve analysis was used to investigate the ability of PET/CT to differentiate malignant lesions from benign tumors.
Results: The malignant and benign groups comprised 64 and 26 patients, respectively. Despite the similarity in the size of primary tumors (P = 0.588), the mean maximum standardized uptake values (SUVmax) obtained from PET/CT imaging were significantly higher in malignant lesions (9.36 ± 5.9) than those of benign tumors (1.04 ± 2.6, P < 0.001). ROC analysis showed that the optimal SUVmax cutoff value for differentiating malignant lesions (to an accuracy of 91%; 95% confidence interval, 83%?98%) from benign tumors was 3.9 (sensitivity, 92.2%; specificity, 84.6%).
Conclusion: PET/CT evaluation of pancreatic lesions confers advantages including fine assessment of malignant potential with high sensitivity and accuracy using a threshold SUVmax value of 3.9.
|
|
|
KEYWORD
|
|
|
Chronic pancreatitis, Pancreas, Pancreatic neoplasms, Pancreatic pseudocyst, Positron emission tomography computed tomography
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
   
|